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Eisbach Bio receives government grant to progress COVID-19 antiviral through Phase I/II clinical development
MUNICH, Germany. April 16th, 2021 – Eisbach Bio, a biotechnology company targeting the molecular machines that drive human disease today announced additional financial support from the German Ministry for Education and Research (BMBF) for the clinical development of its first-in-class SARS-CoV-2 helicase inhibitor. Leveraging Eisbach’s proprietary drug discovery platform, the company has concluded preclinical development of its candidate molecule. Eisbach and 7 additional German companies were awarded BMBF funding to support the clinical development of novel COVID-19 therapeutics, as announced by the Federal Minister for Education and Research, Ms. Anja Karliczek.
Eisbach’s CEO, Dr. Adrian Schomburg, commented: “We are very thankful to receive BMBF support to clinically validate our once-a-day remedy. The tablets are easy to manufacture and distribute, offering the potential to alleviate disease symptoms and globally reduce COVID-19 hospitalizations and deaths.” Prof. Andreas Ladurner, Eisbach’s CSO, added: “Our drug blocks viral replication through a novel, targeted mechanism that is fully conserved across all known virus variants. We are determined to deliver a sustainable medicine with a safety profile that should allow anybody testing positive for SARS-CoV-2 to take this medicine.”
The antiviral adds to the company’s strong oncology pipeline, consisting of first-in-kind inhibitors for two synthetic-lethal cancer targets. Eisbach is rapidly progressing its IND-enabling work and expects to initiate Phase I clinical trials for its COVID-19 asset in Q3 2021.
About Eisbach Bio GmbH:
Eisbach develops novel drugs that disrupt molecular machines essential to tumors with defined genetic vulnerabilities in the context of DNA damage and repair (DDR). Its proprietary platform creates targeted therapies that exploit disease-relevant vulnerabilities. By shutting off the machine’s engine using allosteric inhibitors, their impactful medicines prevent the reorganization and evolution of cancer genomes. Founded in 2019, Eisbach is privately held and backed by international investors. For more information, please visit www.eisbach.bio.
Link to BMBF press release